Persistent neuromuscular disorders associated with changes in tibialis anterior and gastrocnemius lateralis muscle architecture in long-covid: an observational longitudinal study.

ABSTRACT: Long COVID-19 causes complications, affecting quality of life and work capacity. However, its long-term impact on lower limb neuromuscular function remains unclear. To evaluate neuromuscular electrophysiological disorders (NEDs) and muscle architecture of the tibialis anterior (TA) and triceps surae (TS) in individuals with moderate or severe COVID-19 compared to control group over 12 months. Seventy participants were divided into moderate-COVID (n = 22), severe-COVID (n = 18), and control (n = 30) groups. COVID groups underwent four assessments over one year. NEDs in the TA and gastrocnemius lateralis (GL) were assessed via stimulus electrodiagnostic testing, while TA and TS muscle architecture was evaluated using ultrasound. Participants with severe-COVID exhibited significantly higher c

SUBMITTER: da Silva Almeida I 

PROVIDER: S-EPMC12491548 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature