A multidimensional analysis of the risk of infection with Ehrlichia canis among urban dogs in Iquitos, Peru.

ABSTRACT: Ehrlichia canis is a tick-borne bacterium that causes a potentially fatal disease in dogs called canine monocytic ehrlichiosis. In this cross-sectional study, we used a One Health framework to identify statistical associations between E. canis infection in dogs and multiple dog-related, human and environmental factors in Iquitos, Peru. Due to the lack of consensus regarding the positivity threshold for E. canis qPCR assays, we also evaluated if the factors associated with infection remained conserved regardless of the Ct value cut-off used: Ct < 35, a conservative but commonly accepted Ct cut-off for bacterial screening, or Ct ≤ 40, which has been used in several E. canis studies. Under the more conservative scenario, we found that the prevalence of E. canis among dogs was 19.6% (95% CI 15

SUBMITTER: Ferradas C 

PROVIDER: S-EPMC12491590 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature