Clinical experience implanting a miniature externally powered vagus nerve stimulator.

ABSTRACT: Vagus nerve stimulation (VNS) is widely used to treat various neurological and psychiatric conditions, including epilepsy and treatment-resistant depression, as well as to enhance motor rehabilitation following stroke. Conventional VNS devices have demonstrated reliability over decades of use, though recent advancements in technology offer new opportunities to further enhance the device. Many emerging indications require only intermittent stimulation, allowing for the development of a miniature externally powered implantable stimulator (MEPS) that is approximately 50 times smaller than conventional devices, is implanted with a single incision, has no battery or leads, and enables paired stimulation. Our observations compiled from three clinical trials with the MEPS device tested the hypoth

SUBMITTER: Epperson JD 

PROVIDER: S-EPMC12491804 | biostudies-literature | 2025 Sep

REPOSITORIES: biostudies-literature