Factors associated with accepting chemotherapy despite the risk of fertility loss in Latin American breast cancer patients-LACOG 0414 study.

ABSTRACT:

Background

Fertility loss due to chemotherapy is a major concern for young patients with breast cancer (BC), influencing treatment decisions and quality of life. Despite established guidelines recommending fertility counseling, access to fertility preservation remains limited in Latin America.

Objectives

This study evaluated attitudes and preferences regarding fertility-related concerns and chemotherapy decision-making among young Latin American women with early-stage BC.

Design

A prospective cohort study was conducted at seven institutions in Brazil, Mexico, and Peru.

Methods

Premenopausal women aged 18-40 years with stage I-III BC requiring (neo)adjuvant chemotherapy completed a fertility questionnaire before treatment, along with validated quality-of-life as

SUBMITTER: Werutsky G 

PROVIDER: S-EPMC12491814 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature