Trajectories of Angina After Initial Invasive vs Conservative Strategy for Chronic Coronary Disease.

ABSTRACT:

Background

Clinical trials typically report average health status outcomes by treatment at single points in time, as opposed to participants' trajectories (or journeys) over time. Although ISCHEMIA (International Study of Comparative Health Effectiveness with Medical and Invasive Approaches) demonstrated better mean health status at discrete times with an invasive treatment among those with baseline angina, the patterns of individual participants' angina over time are unknown.

Objectives

The purpose of this study was to identify patterns of individual participants' angina over time after invasive or conservative management strategies for chronic coronary disease.

Methods

In this secondary analysis of the ISCHEMIA trial, which enrolled participants with chronic coronar

SUBMITTER: Ikemura N 

PROVIDER: S-EPMC12492302 | biostudies-literature | 2025 Sep

REPOSITORIES: biostudies-literature