Association of arsenic exposure with PDGF-BB in vitro and in a South Texas population exposed through drinking water.

ABSTRACT: Exposure to arsenic (As) from drinking water is a global public health concern, as As is a recognized carcinogen. Groundwater in South Texas, particularly in areas with Gulf Coast aquifers, contains high levels of As. Private wells are neither regulated nor regularly monitored, leaving residents vulnerable to arsenic exposure. This study aimed to investigate potential biomarkers of health effects for long-term, low-level As exposure among private well users in South Texas and to cross-validate findings using an in vitro model. Among 74 private well users, the association between urinary As levels and urinary LDH and 16 cytokine levels was assessed. After adjusting for covariates, linear regression analysis showed weak but significant associations between urinary total inorganic As levels a

SUBMITTER: Svetlik AE 

PROVIDER: S-EPMC12492440 | biostudies-literature | 2025 Jun

REPOSITORIES: biostudies-literature