Investigate gantry position error effect on dynamic spot-scanning proton arc (SPArc) therapy.

ABSTRACT: Objective.Spot-scanning proton arc therapy (SPArc) enables dynamic dose delivery through continuous gantry rotation, offering potential improvements in dose conformity for complex targets. However, dynamic delivery introduces susceptibility to gantry position errors (GPEs), which may degrade the treatment accuracy, particularly in highly precise and conformal techniques. This study aims to quantitatively assess the dosimetric impact of systematic and random GPEs during the dynamic SPArc delivery.Method.Twolve clinical cases, including brain stereotactic radiosurgery (SRS), lung, liver, and prostate cancer, were evaluated under simulated systematic and random GPEs with ±0.5°, ±.1°, ±1.5°, ±2° per 180° arc scenarios. SPArc plans were generated using a published algorithm implem

SUBMITTER: Liu P 

PROVIDER: S-EPMC12492475 | biostudies-literature | 2025 Sep

REPOSITORIES: biostudies-literature