Prognostic significance of abdominal aortic calcification scores on dual-energy X-ray absorptiometry scans for mortality in cancer survivors: NHANES-based cohort study (2013-2019).

ABSTRACT:

Aims

Abdominal aortic calcification (AAC) is a marker of systemic atherosclerosis associated with adverse cardiovascular (CV) outcomes in the general population. This study aimed to evaluate the association of AAC with all-cause and CV mortality in cancer survivors.

Methods and results

Using 7 years of data from the National Health and Nutrition Examination Survey (NHANES, 2013-2019), we analysed a nationally representative cohort of US cancer survivors. AAC burden was quantified using the Kauppila AAC-24 scores on dual-energy X-ray absorptiometry (DXA) scans. Kaplan-Meier curves and multivariable Cox models were used to assess the associations between AAC and all-cause mortality, while Fine and Gray models assessed associations between AAC and CV mortality, accounting for n

SUBMITTER: Al-Jarshawi M 

PROVIDER: S-EPMC12492483 | biostudies-literature | 2025 Sep

REPOSITORIES: biostudies-literature