Stability study of common vasoactive drugs diluted in five types of solutions.

ABSTRACT:

Background

Vasoactive drugs are widely used during the perioperative period. Different vasoactive drugs have specific recommended solutions for dilution as stated in their instructions, but non-recommended solutions are sometimes used in clinical practice. The impact of using non-recommended solutions on drug stability remains unclear. This study investigated the stability of various commonly used vasoactive drugs diluted with five commonly used solutions-0.9% sodium chloride injection, sodium lactate Ringer's injection, glucose sodium chloride injection, 5% glucose injection, and 10% glucose injection-under room temperature (24 °C ± 1 °C) without light protection.

Methods

Each drug was diluted to clinically common concentrations using the five solutions mentioned above. Fiv

SUBMITTER: Yang H 

PROVIDER: S-EPMC12492491 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature