Prognostic factors of locally advanced cervical cancer after concurrent chemoradiotherapy: a retrospective study.

ABSTRACT:

Objective

To investigate the prognostic value of magnetic resonance imaging (MRI) features and clinical features in locally advanced cervical cancer (LACC) patients after concurrent chemoradiotherapy (CCRT).

Methods

A total of 189 patients with LACC who received definitive CCRT between May 2018 and December 2020 and underwent MRI, including diffusion-weighted imaging, before and 1 month after initial therapy were recruited for this study. The tumor size and mean apparent diffusion coefficient (ADC_mean) were evaluated. A Cox proportional hazards model and univariate and multivariate analyses were used to determine the associations of clinical characteristics and imaging factors with progression-free survival (PFS) and overall survival (OS).

Results

The media

SUBMITTER: Li X 

PROVIDER: S-EPMC12492540 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature