Evaluation of oxidative stress markers and the angiogenic factors in preeclampsia and associated features.

ABSTRACT:

Background

Preeclampsia (PE) is a complex hypertensive pregnancy disorder with a multifaceted aetiology. The current study focuses on determining the role of potent oxidative stress markers and sEng in susceptibility to PE, as well as investigating the morphometric and histopathological alterations induced in the fetal membranes of women with PE.

Methods

The current case-control study involves 200 participants, 100 with Preeclampsia and 100 normotensive control women. A total of 200 urine (PE/Control = 100), 200 blood (PE/Control = 100), 200 placenta (PE/Control = 100), and 100 fetal membrane samples (PE/Control = 50) were collected. Urine samples were analysed to measure protein concentrations. Reactive oxygen species (ROS), thiobarbituric acid reactive substances (TBARS),

SUBMITTER: Tariq M 

PROVIDER: S-EPMC12492581 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature