Complete genome sequencing, molecular and antigenic characterization of duck hepatitis A virus type 1 isolated in Benha, Egypt.

ABSTRACT:

Background

Duck virus hepatitis (DVH) is highly fatal disease that predominantly affects young ducklings, causing substantial losses due to its high morbidity and mortality rates. A severe outbreak occurred in young Pekin ducklings on a commercial farm in Benha, Egypt.

Results

The affected birds exhibited neurological signs, including lethargy, ataxia, and opisthotonus, leading to a high mortality rate. The livers and kidneys of ducklings showed various degrees of gross and histopathological lesions. Virus isolation trials in embryonated duck eggs revealed the characteristic greenish discoloration of the allantoic fluid, along with hepatitis and embryonic mortality. Furthermore, RT-PCR confirmed the presence of suspected duck hepatitis A virus type 1(DHAV-1). This study pres

SUBMITTER: Moharam I 

PROVIDER: S-EPMC12492683 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature