Intergenerational Transmission of Cannabis Use: Testing Genetic Risk and the Mitigating Influences of Parent Positive Behavior Support in Early Childhood.

ABSTRACT: As the prevalence of Cannabis Use Disorder (CUD) in late adolescence increases, understanding the etiology of CUD is paramount. Consistent with resilience frameworks, the current study examined whether parent cannabis use and genetic risk predicted offspring cannabis use and CUD symptoms in late adolescence. Parental positive behavior support in early childhood was considered as a possible buffer of intergenerational transmission and genetic risk for CUD. The sample consisted of 731 18-year-olds (M = 18.74, SD = 0.50; 50.2% female, 49.8% male; 50% White, 28% Black, 13% Hispanic, 9% Indigenous, Native Hawaiian, or Asian) from the Early Steps Multisite Study. Parent cannabis use was measured at offspring ages 2, 3, 4, 5, 7.5, 8.5, and 9.5, and observational positive behavior support was meas

SUBMITTER: Ostner SG 

PROVIDER: S-EPMC12492698 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature