Environmental and occupational risk factors associated with multiple myeloma: a multicenter, hospital-based, matched case-control study.

ABSTRACT:

Introduction

Multiple myeloma (MM), a hematologic malignancy driven by neoplastic plasma cell proliferation, remains insufficiently characterized with respect to occupational and environmental risk factors and their impact on patients' quality of life (QoL). This study explores modifiable exposures in the West Bank, Palestine, and evaluates their associations with MM risk and disease-specific QoL outcomes.

Methods

A multicenter, hospital-based case-control study was conducted between 2018 and 2025, including 227 MM patients and 176 matched controls. Matching was based on age, sex, hospital setting, and admission type. Occupational/environmental exposures including ionizing radiation, cosmetics-related agents, pesticides, organic solvents, and farming were assessed via struct

SUBMITTER: Alnees M 

PROVIDER: S-EPMC12492709 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature