Association between volatile organic compounds in urine and dyslipidemia: findings based on analysis of NHANES data.

ABSTRACT:

Background

Evidence linking urinary metabolites of volatile organic compounds (UMVOCs) to dyslipidemia remains limited and scarce. This research sought to thoroughly clarify the UMVOCs-dyslipidemia associations and evaluate the inflammation's mediating effect in this association.

Methods

Nationally representative data (from 6,962 enrolled participants) obtained from the National Health and Nutrition Examination Survey (NHANES) formed the basis of this analysis. We applied weighted logistic regression models for the assessment of relationship between individual UMVOC exposure and dyslipidemia, and weighted quantile sum (WQS) regression for the evaluation of the impact of co-exposure to multiple mixed UMVOCs on dyslipidemia. We performed mediation analysis for investigation in

SUBMITTER: Wu L 

PROVIDER: S-EPMC12492794 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature