Global, regional, and national childhood brain and central nervous system cancer burden: an analysis based on the Global Burden of Disease Study.

ABSTRACT:

Objectives

We assessed the global, regional, and national burdens of childhood brain and central nervous system cancer from 1990-2021 (the latest year).

Methods

We utilized data from the 2021 Global Burden of Disease Study and analyzed trends in childhood brain and central nervous system cancers through joinpoint regression. We assessed the global burden of childhood brain and central nervous system cancers from various perspectives. Finally, the Bayesian age‒period‒cohort model was employed to forecast future trends through 2030.

Results

Childhood brain and CNS cancers are the most common solid tumors and the leading cause of death in children. From 1990 to 2021, the age-standardized incidence, prevalence, mortality, and DALYs decreased. The incidence is slightly gre

SUBMITTER: Su Z 

PROVIDER: S-EPMC12492830 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature