Phenotypic and safety exploration of indigenous bacterial strains for probiotic applications in aquaculture.

ABSTRACT: Quorum-sensing (QS) interference is a promising antivirulence strategy in aquaculture. This study investigated six indigenous bacterial strains for their ability to degrade N-hexanoyl homoserine lactone, a key QS signaling molecule. All strains demonstrated significant QS interference, indicating potential as biocontrol agents. Furthermore, we assessed the key in vitro traits relevant to probiotic application. These included growth rate, pH tolerance and salinity resilience. MYUG presented the fastest growth, followed by KSNUG, PMUG01, LFUG, PMUG02, and HSNUG, representing promising establishment potential within production systems and in fish guts. All strains tolerated pH (3-9) and salinity (1%-4%), supporting their adaptability to aquaculture environments and dynamic GIT conditions. Gly

SUBMITTER: Rwezawula P 

PROVIDER: S-EPMC12492942 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature