Movement Disorders in Toxoplasmosis: A Systematic Review.

ABSTRACT:

Background

Movement disorders are an uncommon but important manifestation of central nervous system toxoplasmosis. Their phenotypes, lesion patterns, and outcomes have not been systematically characterized.

Methods

A PRISMA-based systematic review identified all published patient-level reports of central nervous system toxoplasmosis with movement disorders. Eligible case reports and case series confirmed infection via serology, neuroimaging, polymerase chain reaction, or histopathology. Extracted data included demographics, immune status, clinical and neuroimaging features, lesion location, movement disorder type, treatment, outcomes, and proposed mechanisms. Cases were classified as hyperkinetic, hypokinetic, or cerebellar/ataxia syndromes and summarized descriptively.

R

SUBMITTER: Garg RK 

PROVIDER: S-EPMC12493030 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature