Extracellular vesicles as biomarkers for endometrial cancer - A systematic review.

ABSTRACT:

Background

The current method for diagnosing endometrial cancer and monitoring treatment response is invasive and fraught with both interobserver and intraobserver variability. Less invasive and more reproducible methods are desirable. This systematic review examines the evidence for extracellular vesicles as minimally invasive biomarkers for endometrial cancer.

Methods

PubMed, Embase and Web of Science were searched for studies reporting extracellular vesicles as biomarkers in females with endometrial cancer. Risk of bias was assessed using the QUADAS-2 tool. A descriptive synthesis of biomarkers reported in the included studies was conducted.

Results

Of the 680 unique records reviewed, 23 studies were included. All 23 studies investigated extracellular vesicles as d

SUBMITTER: Baxter E 

PROVIDER: S-EPMC12493225 | biostudies-literature | 2025 Sep

REPOSITORIES: biostudies-literature