Mumps Seroprevalence in Vellore, South India: A Community-Based Cross-Sectional Study.

ABSTRACT: The mumps vaccine remains excluded from India's National Immunization Schedule (NIS) because of insufficient data on the community-level disease burden, despite mumps being a vaccine-preventable disease. In the present study, biobanked serum samples from an urban population in Vellore, stratified by age (in age groups of 1-5, 6-15, and 16-40 years) and sex, were tested for anti-mumps IgG antibodies using ELISA. The seroprevalence rates of mumps were 26%, 71%, and 84% in the 1- to 5-year, 6- to 15-year, and 16- to 40-year age groups, respectively, indicating a high burden in the community. Women in the 16- to 40-year age group exhibited a higher seroprevalence compared with males, with antibody levels consistently lower in males across both the 6- to 15-year and 16- to 40-year age groups (P

SUBMITTER: Madhavan R 

PROVIDER: S-EPMC12493236 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature