Lung transplantation outcomes of patients with interstitial pneumonia with autoimmune features: a single-centre retrospective cohort study.

ABSTRACT:

Objective

Interstitial pneumonia with autoimmune features (IPAF) describes patients with interstitial lung disease (ILD) and autoimmune features without meeting criteria for a specific rheumatic disease. No longitudinal data exist on post-transplant outcomes in IPAF patients. We compared baseline demographics, pre-transplant characteristics and post-transplant outcomes between IPAF and idiopathic pulmonary fibrosis (IPF) patients undergoing double lung transplantation.

Methods

We retrospectively analysed lung transplant recipients with ILD in British Columbia between 1 January 2014 and 30 April 2024. Diagnoses of IPAF and IPF were made by multidisciplinary review. Continuous variables were analysed using the Mann-Whitney U test, categorical variables with Fisher's exact test

SUBMITTER: Yu ACM 

PROVIDER: S-EPMC12494216 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature