Does body composition matter in patients with systemic sclerosis?

ABSTRACT:

Objectives

Body composition plays a significant role in various rheumatic and autoinflammatory diseases. The aim of our study was to assess the impact of muscle mass and subcutaneous adipose tissue quality and quantity in patients with SSc.

Methods

Adults with SSc referring to our tertiary centre who underwent high-resolution chest CT (HRCT) to assess pulmonary involvement were included. A semi-automatic segmentation of the subcutaneous fat and paravertebral muscle was performed at the level of the 12th dorsal vertebra, and body composition metrics were collected (subcutaneous fat and paravertebral muscle area and density). Stepwise linear regression analysis was applied to evaluate if body composition, demographics and pulmonary function tests acted as predictors of mortali

SUBMITTER: Giraudo C 

PROVIDER: S-EPMC12494221 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature