Assessing anemia in stroke patients through virtual non-contrast imaging with photon-counting detector CT: validation on supra-aortic vessel CT-Angiography.

ABSTRACT:

Background and purpose

Anemia is a common comorbidity in stroke patients, traditionally detected via blood tests. This study evaluates the feasibility of using virtual non-contrast (VNC) imaging from photon counting detector-CT (PCD-CT) angiography to detect anemia and identifies the optimal anatomical site for assessment.

Materials and methods

In this retrospective study of 80 patients undergoing PCD-CT angiography of supra-aortic vessels, VNC series were analyzed at various anatomical sites, including the jugular veins, aorta, and cerebral sinuses. Correlations between serum hemoglobin (Hb) levels and VNC Hounsfield Unit (HU) values were assessed using Pearson's coefficients. Linear regression and ROC analysis evaluated diagnostic performance.ResultsThe jugular veins showe

SUBMITTER: Quint GA 

PROVIDER: S-EPMC12494657 | biostudies-literature | 2025 Aug

REPOSITORIES: biostudies-literature