Similarity in Early Life Stress Exposure Is Associated With Similarity in Neural Representations in Early Adulthood.

ABSTRACT: Early life stress (ELS) has profound implications for developmental trajectories, yet the neural mechanisms underlying its long-term effects remain incompletely understood. In the present study, we examined whether interindividual similarity in ELS exposure aligns with similarity in neural representations and behavioral task performance in early adulthood. Leveraging a 20-year longitudinal dataset of Finnish families, we evaluated 87 young adults who underwent functional magnetic resonance imaging (fMRI) during an emotional go/no-go task. Intersubject representational similarity analysis (IS-RSA) was used to assess the associations between pairwise similarities in prospectively or retrospectively measured ELS, neural representations in 360 cortical regions, and task performance. We incorpo

SUBMITTER: Ilomaki M 

PROVIDER: S-EPMC12495272 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature