Synthesis of nanoparticles of cobalt protoporphyrin IX (Co(iii)PPIX NPs). Antiradical, cytotoxicity and antibacterial properties.

ABSTRACT: Porphyrins, composed of a tetrapyrrolic core and various substituents, are highly valued for their photo-, catalytic, electrochemical, and biochemical properties. Protoporphyrin IX (PPIX) is a heterocyclic organic compound whose porphyrin ring enables the chelation of transition metals, resulting in metalloporphyrins with diverse biological functions. Cobalt protoporphyrin IX (Co(iii)PPIX) is known as an inducer of heme oxygenase-1 (HO-1) and has been identified as a potential photosensitiser for use in photodynamic cancer therapy. In this study, Co(iii)PPIX nanoparticles (NPs) were synthesised via the antisolvent method. The resulting NPs were thoroughly characterised using FTIR spectroscopy, Raman spectroscopy, UV-Vis spectroscopy, DLS, SEM, and EDX techniques. Furthermore, their

SUBMITTER: Fijalkowski P 

PROVIDER: S-EPMC12495410 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature