Surgery for pineal cysts with symptoms in the absence of hydrocephalus: a prospective cohort study.

ABSTRACT:

Background

There is mounting evidence for surgery as an effective treatment in selected patients with non-hydrocephalic symptomatic pineal cyst (nhSPC) syndrome. We present the first prospective cohort study of surgical PC resection to treat nhSPC syndrome.

Methods

CamProS-PC is an observational, single-centre, prospective cohort study. Patients were eligible if aged >18 years, PC size >10 mm, had severe symptoms refractory to medical treatment, without ventriculomegaly. Patient-reported data were collected preoperatively, and 3 and 12 months postoperatively. MR imaging was performed before and 12 months after surgery. The primary outcome was improvement in Role Functioning (RF) at 12 months. Secondary outcomes were changes in other domains of Health-Related Quality of Life

SUBMITTER: Masina R 

PROVIDER: S-EPMC12495433 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature