Cost-Utility Analysis of Accelerated and Standard Strategies for Renal Replacement Therapy Initiation.

ABSTRACT:

Importance

Little is known about the long-term costs and outcomes related to strategies for timing of initiation of kidney replacement therapy (KRT) in critically ill patients with severe acute kidney injury (AKI).

Objective

To estimate the cost-utility and cost-effectiveness of accelerated KRT initiation compared with standard KRT initiation in critically ill patients with AKI.

Design, setting, and participants

In this economic evaluation, a state-transition model was developed using data from the Standard vs Accelerated Initiation of Renal Replacement Therapy in AKI (STARRT-AKI) trial, a multicenter, multinational randomized clinical trial of critically ill patients with severe AKI conducted between October 2015 and September 2019. Trial data were linked to administ

SUBMITTER: Round J 

PROVIDER: S-EPMC12495491 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature