GH97 is a new family of glycoside hydrolases, which is related to the alpha-galactosidase superfamily.

ABSTRACT:

Background

As a rule, about 1% of genes in a given genome encode glycoside hydrolases and their homologues. On the basis of sequence similarity they have been grouped into more than ninety GH families during the last 15 years. The GH97 family has been established very recently and initially included only 18 bacterial proteins. However, the evolutionary relationship of the genes encoding proteins of this family remains unclear, as well as their distribution among main groups of the living organisms.

Results

The extensive search of the current databases allowed us to double the number of GH97 family proteins. Five subfamilies were distinguished on the basis of pairwise sequence comparison and phylogenetic analysis. Iterative sequence analysis revealed the relationship of the G

SUBMITTER: Naumoff DG 

PROVIDER: S-EPMC1249566 | biostudies-literature | 2005 Aug

REPOSITORIES: biostudies-literature