Genome annotation of Anopheles gambiae using mass spectrometry-derived data.

ABSTRACT:

Background

A large number of animal and plant genomes have been completely sequenced over the last decade and are now publicly available. Although genomes can be rapidly sequenced, identifying protein-coding genes still remains a problematic task. Availability of protein sequence data allows direct confirmation of protein-coding genes. Mass spectrometry has recently emerged as a powerful tool for proteomic studies. Protein identification using mass spectrometry is usually carried out by searching against databases of known proteins or transcripts. This approach generally does not allow identification of proteins that have not yet been predicted or whose transcripts have not been identified.

Results

We searched 3,967 mass spectra from 16 LC-MS/MS runs of Anopheles gambiae sal

SUBMITTER: Kalume DE 

PROVIDER: S-EPMC1249570 | biostudies-literature | 2005 Sep

REPOSITORIES: biostudies-literature