Analysis of the analgesic mechanism of TENS-WAA in colonoscopy using the EEG-fNIRS system: a study protocol for a randomised controlled trial.

ABSTRACT:

Introduction

Colonoscopy is an essential procedure for the early diagnosis of colorectal conditions; however, over 60% of patients undergoing non-sedated colonoscopy report moderate to severe pain. This study aims to investigate the central analgesic mechanisms of transcutaneous electrical nerve stimulation based on wrist-ankle acupuncture theory (TENS-WAA). A multimodal approach combining electroencephalography (EEG) and functional near-infrared spectroscopy (fNIRS) will be employed to assess pain-related brain activity, with artificial intelligence applied to model the relationship between objective neurophysiological signals and subjective pain experience.

Methods

This is a single-centre, randomised, double-blind, controlled trial involving 60 patients undergoing colonosc

SUBMITTER: Wang H 

PROVIDER: S-EPMC12496052 | biostudies-literature | 2025 Sep

REPOSITORIES: biostudies-literature