Associations between gestational diabetes mellitus and survival without bronchopulmonary dysplasia in very preterm infants: a multicentre cohort study.

ABSTRACT:

Objective

To investigate whether gestational diabetes mellitus (GDM) was associated with survival without bronchopulmonary dysplasia (BPD) in very preterm infants (VPIs).

Design

Retrospective multicentre cohort study.

Setting

A total of 79 neonatal intensive care units across China, January 2019 to December 2021.

Participants

A total of 23 752 VPIs (<32 weeks' gestation) or very low birth weight infants (<1500 g), comprising 4452 GDM-exposed and 19 300 unexposed infants.

Main outcome measures

The primary outcomes are survival without BPD at 36 weeks' postmenstrual age (PMA) and its components.

Results

Infants exposed to GDM were associated with a higher rate of survival without BPD (aOR 1.12, 95% CI 1.04 to 1.21) at 36 weeks PMA and lower mortalit

SUBMITTER: Lei X 

PROVIDER: S-EPMC12496082 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature