Association between circulating biomarkers and atrial fibrillation burden in patients with paroxysmal atrial fibrillation: a subanalysis of the RACE V study.

ABSTRACT:

Background

Biochemical markers of inflammation, coagulation and myocardial stress have been associated with both prevalent and incident atrial fibrillation (AF), but little is known about the relationship between biomarker expression and AF burden.

Aims

Our aim was to investigate the association between cardiovascular biomarkers and AF burden and AF episode duration ≥24 hours.

Methods and results

In this multicentre observational cohort study, we included 404 patients with paroxysmal AF from the Reappraisal of Atrial Fibrillation: Interaction between Hypercoagulability, Electrical Remodelling and Vascular Destabilisation in the Progression of AF study and evaluated a total of 92 potential cardiovascular blood biomarkers. All patients completed 1 year of follow-up with

SUBMITTER: Frausing MHJP 

PROVIDER: S-EPMC12496087 | biostudies-literature | 2025 Sep

REPOSITORIES: biostudies-literature