The prevalence and risk of mortality associated with antimicrobial resistance within nosocomial settings-a global systematic review and meta-analysis of over 20,000 patients.

ABSTRACT:

Background

Bacterial antimicrobial resistance (AMR) is a leading cause of death globally. However, there has been no data synthesis on whether it influences mortality within hospital settings. We conducted a systematic review and meta-analysis to quantify the prevalence and risk of mortality associated in hospitalised patients with AMR, compared to patients with infections not classified as AMR.

Methods

Databases (MEDLINE, EMBASE, and Cochrane library) were searched from inception up to 14th April 2025 for studies that reported the prevalence of AMR in patients who acquired infections in hospitals and mortality (PROSPERO CRD42023420609). We calculated pooled prevalence estimates of AMR as well as unadjusted and adjusted estimates of the effect of AMR on mortality using a ran

SUBMITTER: George NA 

PROVIDER: S-EPMC12496217 | biostudies-literature | 2025 Sep

REPOSITORIES: biostudies-literature