The impact of expectant management compared with intrauterine insemination with ovarian stimulation on quality of life and coital frequency in couples with unexplained subfertility.

ABSTRACT:

Objective

To study the impact of 6 months of expectant management (EM) compared with 6 months of intrauterine insemination with ovarian stimulation (IUI-OS) on the health-related quality of life (HRQoL), anxiety and depression scores and the coital frequency in couples with unexplained subfertility and a poor prognosis for natural conception.

Design

A study alongside the ExIUI trial, a multicentre randomized controlled trial.

Subjects

Couples with unexplained subfertility and a poor prognosis for natural conception based on the score of Hunault.

Intervention

Women in both groups were asked to fill in the Fertility Quality of Life (FertiQol) and Hospital Anxiety and Depression Scale (HADS) questionnaires at 3 moments and to keep a diary with their periods and da

SUBMITTER: Wessel JA 

PROVIDER: S-EPMC12496428 | biostudies-literature | 2025 Sep

REPOSITORIES: biostudies-literature