High Ferritin Predicts Mortality in Patients With Interstitial Pneumonia and an Underlying Autoimmune Disease.

ABSTRACT:

Purpose

To identify early predictive markers in patients with chronic interstitial pneumonia (IP) associated with an underlying autoimmune disease (AIP), aiming to facilitate personalized follow-up and treatment.

Methods

We assessed the predictive value of process and host factors on mortality in a cohort of 124 patients (86 women) with autoimmune interstitial pneumonia (AIP). This cohort comprised 66 cases of connective tissue disease-associated interstitial pneumonia (CTD-IP), 40 patients with interstitial pneumonia with autoimmune features (IPAF), and 18 patients with undifferentiated autoimmune IP. All patients had a minimum follow-up of 2 years or a fatal outcome. We included demographics, clinical diagnostic subgroups, specific antibodies, morphological patterns, and r

SUBMITTER: Rodriguez-Nieto MJ 

PROVIDER: S-EPMC12496540 | biostudies-literature | 2025 Jul-Sep

REPOSITORIES: biostudies-literature