The effect of omega-3 supplementation on metabolic, inflammatory and oxidative stress biomarkers in pregnant women: a systematic review and meta-analysis.

ABSTRACT:

Background

This meta-analysis evaluates the effects of omega-3 supplementation on metabolic, inflammatory, and oxidative stress in pregnancy women by synthesizing findings from randomized controlled trials (RCTs), as existing evidence remains inconclusive.

Methods

A systematic search was conducted using PubMed, Scopus, and Web of Science until July 2024. Random-effects models were applied to estimate each outcome's standardized mean difference (SMD) and 95% confidence intervals (CI).

Results

A total of 14 studies were included in the meta-analysis. The duration of omega-3 supplementation ranged from 6 to 29 weeks. Omega-3 supplementation did not have a significant effect on FBS (SMD = -0.74, 95% CI: -1.94, 0.45), and insulin (SMD = -0.76, 95% CI: -1.77, 0.24), TC (SMD

SUBMITTER: Saadh MJ 

PROVIDER: S-EPMC12497593 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature