Longitudinal relaxation rate ( R 1 ) in lung: a systematic review and meta-analysis.

ABSTRACT:

Objective

The lung magnetic resonance longitudinal relaxation rate R1 varies with disease but reported values in healthy subjects (HS) also differ markedly between studies.

Objective

To evaluate the reported values and variances of observed R1 accounting for field strength B0 , acquisition method, and disease.

Materials and methods

A systematic literature search was performed to identify studies quantifying R1 or its reciprocal T1 . The relationship between field strength and observed R₁ was analysed in all healthy subject data. Data were fit to the heuristic equation R1=B∗(B0A) . The variances between-study bs , within-study-between-subject wsbs , and within-study-within-subject wsws , in HS were assessed. Linear correlation between observed R₁

SUBMITTER: Edwards L 

PROVIDER: S-EPMC12497672 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature