Anti-<i>Porphyromonas gingivalis</i> lipopolysaccharide antibody in rheumatoid arthritis patients with emphysema.

ABSTRACT:

Objective

Lung diseases that are chronic (emphysema [EMP], airway disease, interstitial lung disease) can complicate rheumatoid arthritis (RA) as extra-articular manifestations. Anti-Porphyromonas gingivalis (P. gingivalis) antibody (Ab) has been analyzed for the diagnosis of periodontal disease and RA patients showed increased anti-P. gingivalis Ab levels. However, amounts of anti-P. gingivalis Ab in RA complicated with chronic lung disease (CLD) are unknown. We measured anti-P. gingivalis Ab in cases of RA with CLD.

Methods

Anti-P. gingivalis lipopolysaccharide (LPS) Ab were measured in RA patient sera by enzyme immunoassay.

Results

Anti-P. gingivalis LPS Ab levels in RA with EMP were significantly lower than in RA ca

SUBMITTER: Oka S 

PROVIDER: S-EPMC12497748 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature