Real-world effect of intermittent calorie-restricted diet on type 2 diabetes remission: a dual-cohort retrospective study.

ABSTRACT:

Aims

Randomized controlled trials (RCTs) have demonstrated that intermittent calorie-restricted diet (ICR) can lead to diabetes remission. We aimed to assess the diabetes remission with ICR among patients with type 2 diabetes (T2D) in real-world settings.

Materials and methods

We performed a retrospective, dual-cohort study (January 2022-July 2023) using real-world data from Chinese patients with T2D. The ICR cohort consisted of 1,069 patients following an intermittent calorie-restricted diet, while the control cohort consisted of 1,099 patients receiving Dietary Guidelines for Diabetes in China (2017 Edition). The primary outcome was diabetes remission. Secondary outcomes included reductions in antidiabetic medication use and changes in fasting blood glucose (FBG). Subgroup

SUBMITTER: Xiao Z 

PROVIDER: S-EPMC12497798 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature