Risk of hematologic malignancies following herpes zoster after COVID-19: a global cohort study.

ABSTRACT:

Introduction

Herpes zoster (HZ) has been reported as a potential post-viral complication in individuals recovering from COVID-19, possibly due to virus-induced immune dysregulation. We aimed to investigate whether post-COVID HZ is associated with an elevated risk of hematologic or infectious complications.

Methods

We conducted a retrospective cohort study using the TriNetX global research network, which aggregates de-identified electronic health records from more than 140 healthcare institutions. Adults diagnosed with COVID-19 between January 2020 and January 2022 were stratified by the presence or absence of HZ within one year of infection and matched 1:1 by age, sex, and comorbidities. Outcomes including leukopenia, urinary tract infection, multiple myeloma, and acute leuk

SUBMITTER: Lu CL 

PROVIDER: S-EPMC12497860 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature