Long-term evolution of white and gray matter structural properties in migraine.

ABSTRACT:

Objective

To elucidate the specific brain changes linked to clinical diagnoses and distinct temporal progression in migraine.

Background

Gray (GM) and white matter (WM) differences were previously identified in chronic migraine (CM) compared to episodic migraine (EM). Regarding GM, patients with CM showed increased cortical thickness in the inferior temporal gyrus, and reduced surface area in the precuneus cortex, superior frontal and temporal gyri, and supramarginal gyrus. In the WM, widespread reduced axial and mean diffusivity have been observed in patients with CM in tracts such as the middle cerebellar peduncle, the internal capsule, the corticospinal tract, and the sagittal stratum. However, no longitudinal studies with a long follow-up have been conducted to comprehen

SUBMITTER: Planchuelo-Gomez A 

PROVIDER: S-EPMC12497938 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature