Efficacy and safety of a digital therapeutic for alcohol dependence: A multicenter, open-label, randomized controlled trial.

ABSTRACT:

Aim

Digital therapeutics (DTx) is an emerging treatment modality for enhancing psychosocial interventions via software programs, such as smartphone applications (apps). We developed a DTx named ALM-003 to support treatment for people with alcohol dependence who are pursuing reduced drinking goals. ALM-003 was designed to promote behavioral change through daily self-monitoring with personalized feedback, interactive psychoeducational modules, and automated treatment support tools for both patients and physicians. In this multicenter, open-label, randomized controlled trial (RCT), we aimed to evaluate the efficacy and safety of ALM-003 in various clinical settings.

Methods

In this RCT, participants with alcohol dependence without serious physical, mental, or social problems du

SUBMITTER: So R 

PROVIDER: S-EPMC12498122 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature