LA-ICP-TOF-MS for quantitative mapping of biogenic carbonate samples using matrix-matched nanoparticulate pressed powder pellets.

ABSTRACT: This study evaluated the micro-homogeneity of seven different commercially available nanoparticulate pressed pellets based on a CaCO₃ matrix and their utility for quantitative elemental mapping of biogenic carbonates using laser ablation-inductively coupled plasma-time-of-flight-mass spectrometry (LA-ICP-TOF-MS). The analytical performance of matrix-matched calibration (using the aforementioned nano-pellets) was compared against that of non-matrix-matched calibration using a silicate glass (NIST SRM 610) reference material for quantification. Calibration with nano-pellets, combined with the use of Ca as an internal standard, significantly improved the quantification accuracy, providing recoveries between 80-120% for the majority of the 18 elements selected and spread across a wi

SUBMITTER: Lores-Padin A 

PROVIDER: S-EPMC12498214 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature