Evaluation of the diagnostic efficacy of different glycemic markers and insulin indices for diabetes mellitus in a general population.

ABSTRACT:

Background

We aimed to assess the contribution of repeated fasting blood glucose (FBG) measurements along with single collection of 2-hour postprandial glucose (2h PG) and glycated hemoglobin (HbA1c) on diabetes mellitus (DM) prevalence estimation, and investigate the association between the insulin-related markers and DM risk in a southeastern Chinese population.

Materials and methods

We included 6515 participants aged 35-75 years with complete glycemic data. McNemar's test was utilized to compare the difference between WHO and ADA criteria in DM diagnosis. Newly diagnosed DM cases were classified as 1defect (DEF), 2DEF, or 3DEF DM according to the abnormalities of three glycemic indices. The sensitivity and specificity of diagnosing DM using different glycemic markers were

SUBMITTER: Gong J 

PROVIDER: S-EPMC12498358 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature