Neuropathic pain development and maintenance and its association with motor recovery after cervical spinal cord injury.

ABSTRACT:

Background

In our published randomized controlled trial, we revealed that patients with acute ASIA Grade C incomplete cervical spinal cord injury (SCI) who underwent early surgery (within 24 h post-injury) had accelerated motor recovery at six months than those with delayed surgery (>2 weeks post-injury); however, neuropathic pain (NeP) worsened regardless of surgery timing. Here, we conducted post-hoc analyses to intensively assess NeP development and maintenance.

Methods

Of 44 patients (median 64.5 years; three female; early intervention, n = 26), NeP was categorized into at-level and below-level pain and evaluated at  two weeks and one year after injury using the Neuropathic Pain Symptom Inventory (NPSI). We compared the two groups based on background charac

SUBMITTER: Saita K 

PROVIDER: S-EPMC12499529 | biostudies-literature | 2025 Jul

REPOSITORIES: biostudies-literature