The association between <i>ADIPOQ</i> gene variants (rs266729, rs2241766, rs1501299) and acute myocardial infarction in Vietnamese patients with type 2 diabetes mellitus.

ABSTRACT:

Background

Type 2 diabetes mellitus (T2DM) significantly increases the risk of acute myocardial infarction (AMI). Polymorphisms in the ADIPOQ gene, which encodes the adiponectin hormone, are believed to influence cardiovascular disease risk. This study aims to evaluate the association between three ADIPOQ gene variants-rs266729, rs2241766, and rs1501299-and the risk of AMI in Vietnamese patients with T2DM.

Methods

A case-control study was conducted from January 2023 to June 2024 at the University Medical Center, Ho Chi Minh City. The study included 275 T2DM patients with a history of AMI (case group) and 275 T2DM patients without AMI (control group). Participants were matched by age, gender, smoking status, and duration of T2DM to control for potential confounding factors. D

SUBMITTER: Le BH 

PROVIDER: S-EPMC12499558 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature