Systematic literature review and meta-analysis of concordance and accuracy of pretransfusion immunohematology routine tests.

ABSTRACT:

Objectives

This study aimed to assess the concordance and comparative accuracy of commercially available immunohematology (IH) tests for pretransfusion testing.

Background

Pretransfusion tests are intended to ensure donor blood is matched with a compatible recipient. Automated testing has become the mainstay since the commercialisation of IH analysers, because of their reduced risk of human error and increased efficiency.

Methods/materials

A systematic literature review (SLR) was performed to identify studies evaluating the concordance and sensitivity/specificity of IH tests for ABO/RhD typing, antibody screening, or antibody identification. Pairwise meta-analysis of concordance and sensitivity/specificity of IH tests was conducted when feasible.

Results

The SL

SUBMITTER: Elliott C 

PROVIDER: S-EPMC12499635 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature