Hepatitis C virus infection in blood donors in Santa Catarina, Brazil, 2010-2020.

ABSTRACT:

Introduction

Hepatitis C is a silent disease characterised by a persistent inflammatory process in the liver. Since blood is the main route of transmission, the objective of this study was to estimate the positivity rate of hepatitis C virus (HCV) infection in blood donations from the Public Blood Network of the State of Santa Catarina and to analyse the temporal trend and spatial distribution of cases between 2010 and 2020.

Methods

This historical cohort study included blood donors who tested positive for HCV and donated blood at the service between January 1, 2010, and December 31, 2020.

Results

Out of a total of 1 316 605 blood donations, 782 new samples tested positive for HCV, corresponding to an overall positivity rate of 59.4 per 100 000 donations. The majority

SUBMITTER: Schuelter-Trevisol F 

PROVIDER: S-EPMC12499645 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature