Prognostic nomogram integrated with inflammatory marker ratios for assessing in-hospital mortality risk in patients with acute type A aortic dissection.

ABSTRACT:

Background

Preoperative inflammatory biomarker ratios to predict adverse outcomes in patients with acute type A aortic dissection (AAD) were assessed in this study, and a prognostic nomogram to guide anti-inflammatory therapy was developed..

Methods

We retrospectively analyzed 673 adult AAD patients who underwent surgery. Preoperative hematological parameters, including neutrophil, lymphocyte, and platelet counts; hemoglobin (Hb) and albumin levels; and composite indices including the neutrophil‒lymphocyte ratio (NLR), platelet‒lymphocyte ratio, neutrophil‒platelet ratio, and platelet‒albumin ratio, were evaluated. The univariate and multivariate logistic regression identified in-hospital mortality predictors, and a nomogram was constructed. The internal validation included

SUBMITTER: Lv XC 

PROVIDER: S-EPMC12500101 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature