DDIAS promotes endometrial cancer progression via β-catenin signaling.

ABSTRACT:

Background

DDIAS has been recognized as an oncogene in various cancers, but its role in endometrial cancer remains unexplored.

Methods

The expression of DDIAS in normal endometrium and endometrial cancer samples was analysed via the The Cancer Genome Atlas (TCGA) database, and prognostic analysis was performed. The differential expression of DDIAS between endometrial cancer and normal endometrium tissues was analyzed using quantitative polymerase chain reaction (qPCR). To study the expression of DDIAS in endometrial cancer, immunohistochemistry was performed on endometrial cancer, atypical endometrial hyperplasia and normal endometrial tissue. The association between DDIAS expression and clinicopathology was analysed. The expression of DDIAS in endometrial cancer cell lines

SUBMITTER: Tian X 

PROVIDER: S-EPMC12500153 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature